Enduro Genetics raises €12 million to unlock the future of scalable bioproduction
Copenhagen, Denmark, February 3rd, 2025
News
Enduro Genetics raises €12 million to unlock the future of scalable bioproduction
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Enduro Genetics is transforming the €400 billion biomanufacturing industry by fundamentally reshaping how microbes behave in bioprocesses
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The patented cell reprogramming technology, Enduro Sense, "addicts" cells to high production and integrates seamlessly into any microbial bioproduction host
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The technology boosts yields, significantly cuts costs, lowers carbon emissions for existing processes, and reduces time-to-market for new products
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Enduro is already working with global biotechnology leaders to transform production, enabling bioproduction at scale
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Funding from Supernova Invest, NOON Ventures and Sandwater will be used to expand Enduro’s platform and scale commercialization
Copenhagen, 3 February 2025: Enduro Genetics – the synthetic biology startup transforming biomanufacturing by “addicting” cells to high production – has raised €12 million in Series A funding from Supernova Invest, NOON Ventures and Sandwater. The funding will be used to expand Enduro’s platform and scale commercialization.
Enduro is addressing a problem that has challenged the global biomanufacturing industry for decades: declining productivity at industrial scale. The estimated €400 billion market, encompassing everything from industrial enzymes, biodegradable materials, alternative proteins, and pharmaceuticals, depends on genetically engineered microorganisms to produce these compounds. Despite best efforts to optimize genetic strains, large-scale industrial processes create conditions that drive microorganisms to mutate, creating “cell-to-cell variation”, as cells prioritize their survival over production industrial processes create
conditions that drive microorganisms to mutate, creating “cell-to-cell variation”, as cells prioritize their survival over production. These non-productive cells proliferate, outcompeting the productive cells for space and nutrients, until ultimately all the productive cells are gone. This causes a significant drop-off in yield over the production cycle, impacting profitability and reducing efficiency.
Universal bioproduction at scale
Enduro’s patented “synthetic addiction” technology, created by founder and CSO Peter Rugbjerg, integrates a genetic plug-in into the microbial production host, coupling each cell’s productivity to its health and growth. This ensures that only high-producing cells can survive and thrive, effectively eliminating non-productive cells from the population. By maintaining a stable and productive microbial community, Enduro Sense unlocks the full potential of industrial biomanufacturing, enabling consistent, scalable, and cost-efficient production. Dr. Rugbjerg’s groundbreaking research into synthetic addiction has been published in Nature and PNAS.
Enduro Sense is applicable for all expression systems where the production confers a burden on the microbial host, irrespective of organism or product type, and can be used in established processes as well as new processes under development. This enables Enduro’s customers to produce existing products more efficiently and drive innovation by accelerating the development and commercialization of new product lines.
Paving the way for a greener, safer, more resilient world
Enduro is commercializing its technology at a pivotal time when industries are embracing biomanufacturing to decarbonize and create sustainable alternatives to fossil-based products, such as bio-based fuels, bioplastics, specialty chemicals, alternative proteins, and pharmaceuticals.
The startup, led by CEO Christian Munch and Rugbjerg, already counts clients including biomanufacturing leaders
from both the biopharma and food, agriculture and industrial space. The new funding takes the total raised by Enduro to €18 million including grants from the BioInnovation Institute and the European Innovation Council accelerator grant, and will be used to expand Enduro’s technology platform and accelerate commercialization.
Christian Munch, CEO of Enduro Genetics said: “This new fundraise is a key milestone for Enduro. It is a testament to the team, the impact potential of our technology and the market validation we have achieved over the last two years. The funding allows us to accelerate our commercialization efforts, strengthen our technology platform and expand the technology for use in biopharmaceutical expression systems, and we are excited to take this next step with the strong backing of both our existing and new investors.”
Peter Rugbjerg, Founder and CSO of Enduro Genetics said: “Solving the cell-to-cell biomanufacturing challenge has plagued academia and industry for decades. Too many companies have been limited by the fact that only a minority of cells used in bioprocesses today contribute to high production. At Enduro, we’re redefining bioprocesses with a new optimization technology to unlock biotechnology’s full potential, which we use to boost already very high-performing processes. This funding allows us to accelerate client adoption and commercialization, and help manufacturers scale sustainably to drive meaningful change in industries that impact us all.”
Romain Sautrau, Investment Director at Supernova Invest said: “Enduro’s novel technology could act as a critical enabler to break the cost barrier of biosolutions for a massive application into the food and chemical industries. We were impressed not only with the technology but also the team's traction in such a short time bringing on board leading biomanufacturing companies. We look forward to working closely with Christian and Peter to support their growth journey.”
Theis Malmborg, General Partner at NOON Ventures said: “We’re delighted to double down on our investment in Enduro in their Series A round. Enduro’s cell reprogramming technology is solving major challenges in the bioproduction space and large organizations are already starting to reap the benefits. We believe the team will have an outsized impact on the future of biomanufacturing, and we are excited to be a part of that journey with them.”
About Enduro Genetics:
Enduro Genetics is a deeptech company transforming biomanufacturing by solving the challenge of microbial productivity. Its patented synthetic addiction technology, Enduro Sense, boosts yields, reduces costs and waste, and enables scalable, sustainable production across biochemicals, alternative proteins, pharmaceuticals, and more. Founded in Denmark, Enduro is helping industries worldwide unlock the full potential of biotechnology for a greener, more sustainable, and more productive future. Enduro was spun out of the Technical University of Denmark, and among others received funding from the BioInnovation Institute and the European Innovation Council Accelerator grant. https://www.enduro.bio/
About Supernova Invest:
Supernova Invest is the leading deeptech Venture Capital firm in Europe and manages c.€800 million in assets. The current portfolio includes 80+ innovative and impact-driven companies that develop products and services leveraging breakthrough technologies in 4 transition-centric sectors: Cleantech, Digital, Industrial Technologies and Healthcare. For 20 years, Supernova Invest has been providing long-term capital, operating experience, and strategic support to back sustainable growth of tomorrow’s deep tech and industrial champions throughout the Venture Capital life cycle: seed, early, late and growth stages. Supernova Invest also gathers the entire deep tech value chain to support portfolio companies: corporates, research institutions and co-investors. Supernova Invest is backed both by Amundi, the largest asset manager in Europe, and CEA, the most innovative public research organization in Europe.
About NOON Ventures:
NOON Ventures is a Danish venture fund that invests in proven, transformative technologies with the potential to be industry-defining while driving meaningful impact on the climate and environment. NOON focuses its investments on a few, carefully selected companies and commits the time and resources needed to help build lasting businesses. One company at a time. www.noon-ventures.com
About Sandwater:
Sandwater is a Nordic-based venture fund investing in early-stage companies and founders who are decoding the world’s toughest problems to accelerate the change we need. Sandwater manages two funds for a total of c.€200 million in assets under management. As a thematic investor with a strong impact mandate, Sandwater specializes in bringing the growth-stage toolbox needed to transform good ideas into great companies. Conviction + experience to get things done. www.sandwater.com
Contact information
For more information about Enduro Genetics, please visit enduro.bio, or get in contact via email: info@endurogenetics.com or by phone: +45 9393 5580.