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About us
VISION
Relying on living organisms, bioproduction can be difficult to scale to large volumes while maintaining titers high. By applying game-changing synthetic biology technology, we empower our partner companies to maximize performance of all cells cultivated from their production strains. By programming cells to maintain high production, we increase competitiveness of current and future green bioproduction.
MISSION
Based in Copenhagen, Denmark, Enduro is an independent service and tech provider committed to improving large-scale fermentations.
What we offer
Enduro Sense
Enduro Sense is a genetic plugin that couples high production levels to growth – effectively making the production strain addicted to the production of the desired product. Enduro Sense has two primary effects:
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Enduro Sense makes the cell population consist of more higher producing cell variants, increasing the baseline yield and titer.
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Enduro Sense maintains the elevated production level throughout the fermentation.
This sustains bio-based production over long time scales and results in higher-producing cells.
Seamless integration
Enduro Sense can be integrated seamlessly into existing, commercial strains or can be used right from the drawing board, providing a flexible approach to scale up of up high-production strains. Enduro Sense does not require any changes to the cultivation medium, ensuring a simple incorporation into existing processes.
Enduro Sense - the future of bioproduction
Biological production exerts a burden on the producing cells. This burden favorizes faster growing lower-producing cells that emerge spontaneously.
Over time, lower-producing cell variants are enriched in the fermentation tank, thereby compromising efficient bio-based production at scale.
Our technology prevents declining production at scale by 'addicting' the cells to high production. We call our technology Enduro Sense and it significantly improves production strain performance – in any organism and at every scale.
Benefits
Higher process yield at scale
Get more out of existing bioprocesses by keeping high-producing strains in the fermentor -increasing yield, titer, rate, and reproducibility.
Enduro Sense is free of antibiotic resistance genes, making handling more compliant, easy and safe.
Antibiotic independence
Enable difficult processes
Production of complex or cellular inhibit products is easier when strain instability is overcome.
Expedited strain development
Enduro Sense accelerates the strain development process through selection of stable and high-producing strains that will succeed during the scale-up phase.
WHAT CAN ENDURO SENSE BE USED FOR?
Conventional bioproduction
EnduroSense
Using Enduro Sense, cells maintain their productive state longer, creating a more homogenous population and higher yield.
Works for all product types
As platform, Enduro Sense is product independent, allowing us to generate plugins that are responsive to most types of bioproducts.
Publications
Articles
pnas.org
Rugbjerg et al, 2018. Synthetic Product Addiction Extends the Productive Lifetime of Engineered Escherichia coli populations. PNAS
Patents
WO2017055360A1 A System For Improved Fermentation Titers
Incl. US11352650B2, US12031170B2
WO2021160854A1 Burden-addicted Production Strains
WO2023021151A1 Burden-addicted Production Strains
Meet the Team
Management
Christian Munch
CEO
Peter Rugbjerg
CSO and Co-founder
Board of Directors
Katherine Mellis
Board Observer
Romain Sautrau
Board Member
Theis Malmborg
Board Member
Thomas Videbæk
Chair Person
Bioprocess Technology
Lara Pauline Munkler
Peter Becker
Science
Anne Line Hartvig
Kira Sarup-Lytzen
Thies Guelck
Christian Munck
Louise Lindbæk
Trine Troensegaard Qvist
Christian Wegener Wistrøm
Nils Myling-Petersen
Victoria Visby Nissen
David Lennox
Rasmus Wied Pedersen
Evelina Fotiou
Rebecca Lennen
Science Support
Alexander Videbæk
Marie Vig Tamstorf
Ece Bahar Yildirim
Vakarė Bachmatavičiūtė
Emelie Riis
Iben Hundebøll Rosenberg
Jakob Weimann
Commercial & Operations
Anke Goormans
Associate Director, Technical Sales
Jacob Steglich-Willert
Associate Director, Business Development
Summer Siman Li
Associate Director
Commercial & Operations Support
Eline Sachse Aaris
Marketing Student Assistant
Johannes Olsson
Junior Business Analyst
Open positions
Project lead in microbial strain engineering
Research scientist in synthetic biology
We always invite unsolicited applications from molecular biology and fermentation scientists here.
If you are interested in an internship or a student project, please contact us with an email subject containing "intern" or "student project".
Recruitment agencies are welcome to submit candidates to Enduro at their own discretion. However, no recruitment fees will be paid unless a written agreement is in place between the recruitment agency and Enduro prior to submission.